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Bacteria in the human body to produce a lot of Medicinal Molecular Analysis: Ye I Source: Kelli Date: 2014-09-15
Studies have shown that bacteria in the human genome and metagenome, the widespread existence of coding sulfur peptide antibiotics (thiopeptide) of BGC. The researchers purified the symbiotic bacteria Lactobacillus gasseri production thiopeptide, will be named lactocillin, and resolve its structure. They found that, lactocillin structure french glamour with some clinical trials have very similar antibiotics can kill some Gram-positive bacteria, while non-destructive to those harmless bacteria. Macro transcriptome sequencing data show, lactocillin and other thiopeptide BGC indeed been expressed in vivo.
Mohamed S. Donia, Peter Cimermancic, Christopher J. Schulze, french glamour Laura C. Wieland Brown, John Martin, Makedonka Mitreva, Jon Clardy, Roger G. Linington, Michael A. Fischbach. A Systematic Analysis of Biosynthetic Gene Clusters in the Human Microbiome Reveals . a Common Family of Antibiotics Cell, 11 September 2014; DOI: 10.1016 / j.cell.2014.08.032
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